This chronic adrenal insufficiency is a rare disease in which the adrenal glands do not generate enough steroid hormones. A characteristic manifestation is a diffuse dark pigmentation of the oral mucosa and skin. Other symptoms may be relatively nonspecific like nausea, anorexia or postural hypotension. In the oral cavity the increased pigmentations can be found solitaire localized or involve nearly the whole mucous membrane. A specific treatment of the pigmentations is not necessary. The oral lesions are likely to disappear as a result of the treatment of the Addison?s disease itself.