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Type II: autoantibody-mediated cytotoxic reactions

For yet unknown reasons, antibodies are produced (Specific IgG or IgM) which turn against the body's own structures instead of foreign matter or parasites. They are called autoantibodies. The antibody-dependant cell-mediated cytotoxicity is activated and leads to the destruction of the afftected cells. Clinical manifestations are hemolytic anemia, thrombocytopenia and neutropenia.

Examples of a type II reaction are autoimmune hemolytic anemias, idiopatic thrombocytopenic purpura or rheumatoid arthritis. back

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Stomatopedia is a free educational platform for stomatology, oral pathology of the soft tissue diseases in children and adolescent. Oral soft tissue diseases exhibit distinctive clinical features and require visual recognition to establish an exact diagnosis. Therefore we share our clinical features with Paedriatricians, Medical Practitioners and Paediatric Dentists and we hope it will be helpful in distinguishing one lesion from another as a part of the diagnostic process. We have set our priority to lesions in children and adolescents and we hope this set focus will stress and develop cooperation. The editors are interested to create a lively exchange about the topics in pictures an in discussion.

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